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Acute kidney injury (AKI), previously called acute renal failure (ARF), denotes a sudden and often reversible reduction in kidney function, as measured by glomerular filtration rate (GFR).[1][2][3] However, immediately after a renal insult, blood urea nitrogen (BUN) or creatinine (Cr) levels may be within the normal range, and the only sign of AKI may be a decline in urine output.


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INTRODUCTION. Acute kidney injury (AKI) is an abrupt and usually reversible decline in the glomerular filtration rate (GFR). This results in an elevation of serum blood urea nitrogen (BUN), creatinine, and other metabolic waste products that are normally excreted by the kidney. In addition, if urine output is also diminished, fluid retention.


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Criteria for AKI. Little progress was made in the understanding of AKI throughout the first two millennia AD. Although the term nephritis dates back to the 16 th century it wasn't really until the late 19 th century that Bright described renal failure (Bright's disease) and included both acute and chronic forms. 4 A century later Bywaters and Beall described "acute renal failure.


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Acute kidney injury (AKI) is recognized as an heterogeneous syndrome affecting short- and long-term morbidity and mortality. Progress on prediction and early detection, clinical phenotypes, pathophysiology, nephrotoxicity, organ cross-talk, prevention and supportive treatment of AKI as well as long-term sequelae are addressed in this review paper.


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Acute kidney injury (AKI), also known as Acute Renal Failure, is a sudden episode of kidney failure or kidney damage that happens within a few hours or a few days. AKI causes a build-up of waste products in your blood and makes it hard for your kidneys to keep the right balance of fluid in your body. AKI can also affect other organs such as the brain, heart, and lungs.


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team. Calculations must be re-checked and should not be used alone to guide patient care, nor should they substitute for clinical judgment. See our full disclaimer. The AKIN Classification for Acute Kidney Injury classifies severity of acute kidney injury, similar to RIFLE Criteria.


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Acute Kidney Injury (AKI) Acute Kidney Injury (AKI) is an acute worsening of kidney function . Globally, AKI is common in patients who are hospitalized for various reasons . The incidence rates of AKI in hospitalized patients vary between 14.7-31.5% . Dehydration and hypotension were recorded as causes in 46% and 38% of patients from LLMICs .